🧠 Exercise slows down aging and neurodegeneration

🧠 How Exercise Keeps the Brain Young 🏃‍♂️🛌🍎

Regular physical activity helps slow aging and protects the brain by boosting metabolism, reducing inflammation, and improving communication between organs like the brain, muscles, and liver.

Published In: European Journal of Medical Research
Date: June 2025
Authors: Kong et al.
Link to Study: Read the full article

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Summary

This review explains how regular exercise supports healthy aging and brain function by improving the way the brain, muscles, and liver work together. Exercise enhances metabolism, reduces inflammation, and protects brain cells—especially important in preventing diseases like Alzheimer’s and Parkinson’s. It also triggers the release of beneficial proteins (like BDNF and IL-6) that support brain health and repair.

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Key Takeaways

✅ Exercise boosts energy metabolism and mitochondrial function in the brain and muscles.
✅ It reduces harmful inflammation linked to aging and neurodegenerative diseases.
✅ Physical activity enhances the release of protective molecules that support learning and memory.
✅ It improves insulin sensitivity and fat metabolism, reducing risk factors for dementia.
✅ Exercise promotes brain cell growth and repairs damage from age-related decline.

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Why It Matters for You

Regular moderate exercise is a powerful way to protect your brain as you age. Adding walks, strength training, or aerobic activity into your routine can help maintain memory, mood, and mental sharpness.

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Citation

Kong, J., et al. (2025). Exercise orchestrates systemic metabolic and neuroimmune homeostasis via the brain–muscle–liver axis to slow down aging and neurodegeneration: a narrative review. European Journal of Medical Research, 30:475. https://doi.org/10.1186/s40001-025-02751-9